Therapeutics

Research studying the use of new and existing drugs for combating the virus

Published and Preprint Papers

Drugs

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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro.

Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19.

convalescent plasma, methylprednisolone

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma.

Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19: A Randomized Clinical Trial.

azithromycin, hydroxychloroquine

COVID-19 outpatients: early risk-stratified treatment with zinc plus low-dose hydroxychloroquine and azithromycin: a retrospective case series study.

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.

hydroxychloroquine

A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.

azithromycin, chloroquine, hydroxychloroquine

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.

Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial.