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Therapeutics

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Research studying the use of new and existing drugs for combating the virus
Published and Preprint Papers
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Drugs
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chloroquine
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.

ivermectin
The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro.

convalescent plasma, methylprednisolone
Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma.

azithromycin, hydroxychloroquine
COVID-19 outpatients: early risk-stratified treatment with zinc plus low-dose hydroxychloroquine and azithromycin: a retrospective case series study.

remdesivir
Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.

hydroxychloroquine
A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.

azithromycin, chloroquine, hydroxychloroquine
Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.

azithromycin, hydroxychloroquine
Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19

hydroxychloroquine
Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19.

azithromycin, hydroxychloroquine
Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19.

Project funded by the Chan Zuckerberg Biohub and NLM grant LM05652