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Model Systems & Tools
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Research proposing new model systems, tools and assays to study the virus
Published and Preprint Papers
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Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.
SARS-CoV-2 productively infects human gut enterocytes.
Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19.
Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform.
Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2.
rhesus macaque
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.
Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice.
Aerosol Exposure of Cynomolgus Macaques to SARS-CoV-2 Results in More Severe Pathology than Existing Models
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.
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