Model Systems & Tools

Research proposing new model systems, tools and assays to study the virus

Published and Preprint Papers

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Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.

SARS-CoV-2 productively infects human gut enterocytes.

Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2.

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform.

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection.

Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice.

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells.

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.