Model Systems & Tools

Research proposing new model systems, tools and assays to study the virus

Published and Preprint Papers

Species

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Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates.

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults.

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.

SARS-CoV-2 productively infects human gut enterocytes.

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge (preprint)/ en

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery.

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform.

Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19.

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.