Model Systems & Tools

Research proposing new model systems, tools and assays to study the virus

Published and Preprint Papers

Species

Title

Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis.

Deglycosylated RBD produced in Pichia pastoris as a low-cost sera COVID-19 diagnosis tool and a vaccine candidate.

Functional assessments of SARS-CoV-2 single-round infectious particles with variant-specific spike proteins on infectivity, drug sensitivity, and antibody neutralization.

Mouse genome rewriting and tailoring of three important disease loci.

Colloidal aggregation confounds cell-based Covid-19 antiviral screens.

Antiviral responses in a Jamaican fruit bat intestinal organoid model of SARS-CoV-2 infection.

Design and validation of an exposure system for efficient inter-animal SARS-CoV-2 airborne transmission in Syrian hamsters.

Improved Culture Methods for Human Coronaviruses HCoV-OC43, HCoV-229E, and HCoV-NL63.

Development of an efficient yeast platform for cannabigerolic acid biosynthesis.

Mammalian cells-based platforms for the generation of SARS-CoV-2 virus-like particles.