Chapter 8 Role of artificial intelligence in fast-track drug discovery and vaccine development for COVID-19

COVID-19 is a global pandemic spread across more than 200 countries and several measures are being taken to control it. Researchers in pharmaceutical academia/industry are incessantly targeting this disease through vaccine and drug development protocols. Artificial intelligence is being extensively explored for surveillance, diagnostics, contact tracing, and for clinical management of COVID-19. The most common application has been for repurposing of existing drugs through various AI tools. Successful training of artificial neural networks based on identification of specific patterns in binding of known antiviral drugs with protein sequences from diverse virus species have generated models giving good predictions for molecules against SARS-CoV-2 virus, in sync with clinical studies. ML tools have also been used to investigate immunogenic components of the virus to be exploited as vaccine candidates. In this chapter, the utilization of artificial intelligence to accelerate drug-design and vaccine design research for COVID-19 has been reviewed.
Date: 31 Dec 2022
DOI: 10.1016/b978-0-323-90054-6.00006-4
Journal: Novel AI and Data Science Advancements for Sustainability in the Era of COVID-19
CORD UID: kt6tnjdl
ML/Curated Information
Viruses: SARS-CoV-2
Article Type(s): Book chapter